HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → 7-[2-(cyclopropylmethoxy)-5-methylphenyl]-2-methyl-N-(1-propanoylpiperidin-4-yl)-1H-pyrrolo[3,2-b]pyridine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | HCID 67774737 | HCID 67774737 | — |
| Product | 7-[2-(cyclopropylmethoxy)-5-methylphenyl]-2-methyl-N-(1-propanoylpiperidin-4-yl)-1H-pyrrolo[3,2-b]pyridine-3-carboxamide | HCID 67775679 | — |
Reaction Steps
Starting from 7-[2-(cyclopropylmethoxy)-5-methylphenyl]-2-methyl-N-(piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridine-3-carboxamide hydrochloride (example D.f18) and commercially available propionyl chloride the title compound is obtained as colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816085B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-e4e2c43fd1e447198310ffe591614ebd |
| Source note | uspto-grants-2014_08 |