Methanesulfonyl chloride → HCID 44222369, compound

HRID 2411131Notes

Reaction equation

HRID 2411131 reaction equation
[NH2:1][C@@H:2]([CH2:5][O:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH2:3]O.[CH3:14][S:15](Cl)(=[O:17])=[O:16]>>[CH2:7]([O:6][CH2:5][C@H:2]1[CH2:3][CH2:14][S:15](=[O:17])(=[O:16])[NH:1]1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 141184082-Amino-3-(benzyloxy)propan-1-ol

Product 1

HCID 44222369HCID 44222369, compound

Procedure

Using (R)-2-amino-3-benzyloxy-1-propanol (2.0 g) and methanesulfonyl chloride (1.8 mL) and by the reaction and treatment in the same manner as in Preparation Example 1, the title compound (370 mg) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 1

Sources & evidence

ORD record
ord-34f5c5a1154e49d3bfcdb1dd7d0806eb
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

Loading…