3-Chloropropanesulphonyl chloride → HCID 71252372, compound

HRID 2411148Notes

Reaction equation

HRID 2411148 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8]C)=[O:7])=[C:4]([N+:12]([O-:14])=[O:13])[CH:3]=1.Cl[CH2:16][CH2:17][CH2:18][S:19](Cl)(=[O:21])=[O:20]>>[O:20]=[S:19]1(=[O:21])[CH2:18][CH2:17][CH2:16][N:1]1[C:2]1[CH:11]=[CH:10][C:5]([C:6]([OH:8])=[O:7])=[C:4]([N+:12]([O-:14])=[O:13])[CH:3]=1

Participants

3

Reactant 2

HCID 154103-Chloropropanesulphonyl chlorideHCID 14730691Methyl 4-amino-2-nitrobenzoate

Product 1

HCID 71252372HCID 71252372, compound

Procedure

Using methyl 4-amino-2-nitrobenzoate (750 mg) and 3-chloropropane-1-sulfonyl chloride (0.61 mL) and by the reaction and treatment in the same manner as in Preparation Example 16, the title compound (967 mg) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 16

Sources & evidence

ORD record
ord-da9d690952bf4772a18f77b9e371dabc
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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