3-Chloropropanesulphonyl chloride → HCID 63190272, compound

HRID 2411150Notes

Reaction equation

HRID 2411150 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8]C)=[O:7])=[CH:4][C:3]=1[F:12].Cl[CH2:14][CH2:15][CH2:16][S:17](Cl)(=[O:19])=[O:18]>>[O:18]=[S:17]1(=[O:19])[CH2:16][CH2:15][CH2:14][N:1]1[C:2]1[CH:11]=[CH:10][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[F:12]

Participants

3

Reactant 2

HCID 154103-Chloropropanesulphonyl chlorideHCID 11182865Methyl 4-amino-3-fluorobenzoate

Product 1

HCID 63190272HCID 63190272, compound

Procedure

Using methyl 4-amino-3-fluorobenzoate (1.12 g) and 3-chloropropane-1-sulfonyl chloride (1.06 mL) and by the reaction and treatment in the same manner as in Preparation Example 16, the title compound (1.04 g) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 16

Sources & evidence

ORD record
ord-8ce93ef81a5f4a6abb4c99cae62c664b
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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