Methanesulfonyl chloride → HCID 11229370, compound

HRID 2411151Notes

Reaction equation

HRID 2411151 reaction equation
[NH2:1][C@H:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:3]O.[CH3:11][S:12](Cl)(=[O:14])=[O:13]>>[C:5]1([C@@H:2]2[CH2:3][CH2:11][S:12](=[O:14])(=[O:13])[NH:1]2)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 2724025(R)-beta-aminophenethyl alcohol

Product 1

HCID 11229370HCID 11229370, compound

Procedure

Using (R)-2-amino-2-phenylethanol (1.37 g) and methanesulfonyl chloride (1.6 mL) and by the reaction and treatment in the same manner as in Preparation Example 1, the title compound (391 mg) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 1

Sources & evidence

ORD record
ord-7d6a527bb71a4b9dafa3589bb2f43f32
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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