3-Chloropropanesulphonyl chloride → HCID 71251963, compound

HRID 2411167Notes

Reaction equation

HRID 2411167 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:13]=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[CH:6][CH:5]=1.Cl[CH2:15][CH2:16][CH2:17][S:18](Cl)(=[O:20])=[O:19]>>[O:19]=[S:18]1(=[O:20])[CH2:17][CH2:16][CH2:15][N:1]1[CH2:2][CH2:3][C:4]1[CH:13]=[CH:12][C:7]([C:8]([O:10][CH3:11])=[O:9])=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 154103-Chloropropanesulphonyl chlorideHCID 11183521Methyl 4-(2-aminoethyl)benzoate

Product 1

HCID 71251963HCID 71251963, compound

Procedure

Using methyl 4-(2-aminoethyl)benzoate (0.78 g) and 3-chloropropane-1-sulfonyl chloride (0.69 mL) and by the reaction and treatment in the same manner as in Preparation Example 17, the title compound (1.00 g) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 17

Sources & evidence

ORD record
ord-27e54c21943141dd96b5e82fa825849b
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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