HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloropropanesulphonyl chloride → methyl (S)-4-[1-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)ethyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloropropanesulphonyl chloride | HCID 15410 | — |
| Reactant | Methyl 4-((1S)-1-aminoethyl)benzoate | HCID 17751895 | — |
| Product | methyl (S)-4-[1-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)ethyl]benzoate | HCID 71261170 | — |
Reaction Steps
Using methyl (S)-4-(1-aminoethyl)benzoate (0.61 g) and 3-chloropropane-1-sulfonyl chloride (0.54 mL) and by the reaction and treatment in the same manner as in Preparation Example 17, the title compound (0.90 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-70fc857922274c519bb0849776f49c26 |
| Source note | uspto-grants-2014_08 |