Ethyl 4-iodobenzoate → HCID 71252759, compound

HRID 2411173Notes

Reaction equation

HRID 2411173 reaction equation
I[C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=1.[CH3:13][C:14]1([CH3:20])[CH2:18][NH:17][C:16](=[O:19])[CH2:15]1>>[CH3:13][C:14]1([CH3:20])[CH2:18][N:17]([C:2]2[CH:12]=[CH:11][C:5]([C:6]([O:8][CH2:9][CH3:10])=[O:7])=[CH:4][CH:3]=2)[C:16](=[O:19])[CH2:15]1

Participants

3

Reactant 2

HCID 142891Ethyl 4-iodobenzoateHCID 6375934,4-Dimethyl-2-pyrrolidinone

Product 1

HCID 71252759HCID 71252759, compoundYield 103.1%

Procedure

Using ethyl 4-iodobenzoate (552 mg) and 4,4-dimethylpyrrolidin-2-one (226 mg) and by the reaction and treatment in the same manner as in Preparation Example 48, the title compound (538 mg) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 48

Sources & evidence

ORD record
ord-f045322ffac34e5280075a369d22d1f8
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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