5-Methyl-2-pyrrolidone → HCID 71252478, compound

HRID 2411174Notes

Reaction equation

HRID 2411174 reaction equation
I[C:2]1[CH:12]=[CH:11][C:5]([C:6]([O:8]CC)=[O:7])=[CH:4][CH:3]=1.[CH3:13][CH:14]1[NH:18][C:17](=[O:19])[CH2:16][CH2:15]1>>[CH3:13][CH:14]1[CH2:15][CH2:16][C:17](=[O:19])[N:18]1[C:2]1[CH:3]=[CH:4][C:5]([C:6]([OH:8])=[O:7])=[CH:11][CH:12]=1

Participants

3

Reactant 2

HCID 660555-Methyl-2-pyrrolidoneHCID 142891Ethyl 4-iodobenzoate

Product 1

HCID 71252478HCID 71252478, compound

Procedure

Using ethyl 4-iodobenzoate (1.70 mL) and 5-methylpyrrolidin-2-one (0.98 g) and by the reaction and treatment in the same manner as in Preparation Example 15, the title compound (1.80 g) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 15

Sources & evidence

ORD record
ord-627a075a16ab449c86342e59236f5d1f
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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