Dimethylhydantoin → HCID 21700179, compound
Reaction equation
[CH3:1][C:2]1([CH3:9])[NH:6][C:5](=[O:7])[NH:4][C:3]1=[O:8].[CH3:10][O:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16]Cl)=[CH:14][CH:13]=1>>[CH3:10][O:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16][N:4]2[C:3](=[O:8])[C:2]([CH3:9])([CH3:1])[NH:6][C:5]2=[O:7])=[CH:14][CH:13]=1Participants
3
Procedure
Using 5,5-dimethylimidazolidine-2,4-dione (3.00 g) and 4-methoxybenzyl chloride (3.81 mL) and by the reaction and treatment in the same manner as in Preparation Example 51, the title compound (4.32 g) was obtained.
Workup
- customby the reaction and treatment in the same manner
- customas in Preparation Example 51
Sources & evidence
- ORD record
- ord-26983c0ab2de41889561165212783301
- Source dataset
- uspto-grants-2014_08
- Patent number
- US08816079B2
Reaction notes
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