2-Oxazolidinone → HCID 28942655, compound

HRID 2411185Notes

Reaction equation

HRID 2411185 reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1.[O:13]1[CH2:17][CH2:16][NH:15][C:14]1=[O:18]>>[O:18]=[C:14]1[N:15]([CH2:2][C:3]2[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=2)[CH2:16][CH2:17][O:13]1

Participants

3

Reactant 2

HCID 739492-OxazolidinoneHCID 256687Methyl 4-(bromomethyl)benzoate

Product 1

HCID 28942655HCID 28942655, compoundYield 87.8%

Procedure

Using methyl 4-bromomethylbenzoate (1.83 g) and oxazolidin-2-one (0.77 g) and by the reaction and treatment in the same manner as in Preparation Example 42, the title compound (1.65 g) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 42

Sources & evidence

ORD record
ord-e43891dd979c4e10923227e0f3ea3724
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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