Methyl 4-(bromomethyl)benzoate → HCID 71261179, compound

HRID 2411186Notes

Reaction equation

HRID 2411186 reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1.[CH3:13][C@@H:14]1[CH2:18][O:17][C:16](=[O:19])[NH:15]1>>[CH3:13][C@@H:14]1[CH2:18][O:17][C:16](=[O:19])[N:15]1[CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 256687Methyl 4-(bromomethyl)benzoateHCID 2734858(R)-4-Methyloxazolidin-2-one

Product 1

HCID 71261179HCID 71261179, compoundYield 74.4%

Procedure

Using methyl 4-bromomethylbenzoate (1.00 g) and (R)-4-methyloxazolidin-2-one (0.49 g) and by the reaction and treatment in the same manner as in Preparation Example 42, the title compound (0.81 g) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 42

Sources & evidence

ORD record
ord-1bb6199f3b9c4ecc84e3819919d606e3
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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