Methyl 4-(bromomethyl)benzoate → HCID 71261184, compound

HRID 2411187Notes

Reaction equation

HRID 2411187 reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1.[CH3:13][C@H:14]1[CH2:18][O:17][C:16](=[O:19])[NH:15]1>>[CH3:13][C@H:14]1[CH2:18][O:17][C:16](=[O:19])[N:15]1[CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 256687Methyl 4-(bromomethyl)benzoateHCID 8063308(S)-4-Methyloxazolidin-2-one

Product 1

HCID 71261184HCID 71261184, compoundYield 80.9%

Procedure

Using methyl 4-bromomethylbenzoate (500 mg) and (S)-4-methyloxazolidin-2-one (243 mg) and by the reaction and treatment in the same manner as in Preparation Example 42, the title compound (440 mg) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 42

Sources & evidence

ORD record
ord-d0edd7bcf5024f0f89b444e8307549dc
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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