2,4-Dinitrobenzoic acid → HCID 86676759, compound

HRID 2411282Notes

Reaction equation

HRID 2411282 reaction equation
[N+:1]([C:4]1[CH:12]=[C:11]([N+:13]([O-])=O)[CH:10]=[CH:9][C:5]=1[C:6]([OH:8])=O)([O-])=O.[CH3:16][C:17]1[CH:22]=[C:21]([CH3:23])[CH:20]=[CH:19][C:18]=1[N:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1>>[NH2:1][C:4]1[CH:12]=[C:11]([NH2:13])[CH:10]=[CH:9][C:5]=1[C:6]([N:27]1[CH2:28][CH2:29][N:24]([C:18]2[CH:19]=[CH:20][C:21]([CH3:23])=[CH:22][C:17]=2[CH3:16])[CH2:25][CH2:26]1)=[O:8]

Participants

3

Reactant 2

HCID 118802,4-Dinitrobenzoic acidHCID 705441-(2,4-Xylyl)piperazine

Product 1

HCID 86676759HCID 86676759, compoundYield 95%

Procedure

Using 2,4-dinitrobenzoic acid (585 mg) and 1-(2,4-dimethylphenyl)piperazine (523 mg) and by the reaction and treatment in the same manner as in Preparation Example 148, the title compound (847 mg) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 148

Sources & evidence

ORD record
ord-8b973afaa207413e956e8aafdf3d285b
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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