HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobenzoic acid → (4-Bromophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobenzoic acid | HCID 11464 | — |
| Reactant | 1-(3,5-Dimethylpyridin-2-yl)piperazine | HCID 58484496 | — |
| Product | (4-Bromophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 71252046 | 90.2% |
Reaction Steps
Using 4-bromobenzoic acid (0.50 g) and 1-(3,5-dimethylpyridin-2-yl)piperazine (0.48 g) described in Preparation Example 79 and by the reaction and treatment in the same manner as in Preparation Example 111, the title compound (0.84 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-76296ab3216545ef9950f832ccb68c97 |
| Source note | uspto-grants-2014_08 |