HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-Fluoro-4-methylpyridine-3-carboxylic acid → [4-(3,5-Dicyclopropylpyridin-2-yl)piperazin-1-yl](6-fluoro-4-methylpyridin-3-yl)methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-Fluoro-4-methylpyridine-3-carboxylic acid | HCID 46739274 | — |
| Edukt | 1-(3,5-Dicyclopropylpyridin-2-yl)piperazine | HCID 58484701 | — |
| Produkt | [4-(3,5-Dicyclopropylpyridin-2-yl)piperazin-1-yl](6-fluoro-4-methylpyridin-3-yl)methanone | HCID 58484583 | 85,5% |
Reaktionsschritte
Using 6-fluoro-4-methylnicotinic acid (0.60 g) and 1-(3,5-dicyclopropylpyridin-2-yl)piperazine (0.92 g) described in Preparation Example 88 and by the reaction and treatment in the same manner as in Preparation Example 111, the title compound (1.23 g) was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08816079B2 |
| Quelldatensatz | uspto-grants-2014_08 |
| ORD ID | ord-fa192ea190e34de99eac0f8f12d02be3 |
| Quellennotiz | uspto-grants-2014_08 |