HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-methanesulfonylbenzoic acid → (4-Bromo-2-methanesulfonylphenyl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-methanesulfonylbenzoic acid | HCID 2761057 | — |
| Reactant | 4-(4-Chlorobenzoyl)Piperidine | HCID 2777115 | — |
| Product | (4-Bromo-2-methanesulfonylphenyl)[4-(4-chlorobenzoyl)piperidin-1-yl]methanone | HCID 67380967 | 98.7% |
Reaction Steps
Using 4-bromo-2-methylsulfonylbenzoic acid (2.8 g) and (4-chlorophenyl)piperidin-4-ylmethanone (2.6 g) and by the reaction and treatment in the same manner as in Preparation Example 109, the title compound (4.8 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-3b690b2050274d72af9a1b27c3d74e9b |
| Source note | uspto-grants-2014_08 |