4-Methyloxybenzyl chloride → HCID 71252435, compound

HRID 2411337Notes

Reaction equation

HRID 2411337 reaction equation
[CH3:1][C@H:2]1[NH:6][C:5](=[O:7])[NH:4][C:3]1=[O:8].[CH3:9][O:10][C:11]1[CH:18]=[CH:17][C:14]([CH2:15]Cl)=[CH:13][CH:12]=1>>[CH3:9][O:10][C:11]1[CH:18]=[CH:17][C:14]([CH2:15][N:4]2[C:3](=[O:8])[C@@H:2]([CH3:1])[NH:6][C:5]2=[O:7])=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 699934-Methyloxybenzyl chlorideHCID 1615267Methylhydantoin-5-(D)

Product 1

HCID 71252435HCID 71252435, compound

Procedure

Using (R)-5-methylimidazolidine-2,4-dione (2.00 g) and 4-methoxybenzyl chloride (2.85 mL) and by the reaction and treatment in the same manner as in Preparation Example 51, the title compound (2.95 g) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 51

Sources & evidence

ORD record
ord-ae3830547fe94acd8bb0e93d7bef89a1
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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