4-Methyloxybenzyl chloride → HCID 71252403, compound

HRID 2411338Notes

Reaction equation

HRID 2411338 reaction equation
[CH3:1][C@@H:2]1[NH:6][C:5](=[O:7])[NH:4][C:3]1=[O:8].[CH3:9][O:10][C:11]1[CH:18]=[CH:17][C:14]([CH2:15]Cl)=[CH:13][CH:12]=1>>[CH3:9][O:10][C:11]1[CH:18]=[CH:17][C:14]([CH2:15][N:4]2[C:3](=[O:8])[C@H:2]([CH3:1])[NH:6][C:5]2=[O:7])=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 699934-Methyloxybenzyl chlorideHCID 6419931Methylhydantoin-5-(L)

Product 1

HCID 71252403HCID 71252403, compound

Procedure

Using (S)-5-methylimidazolidine-2,4-dione (2.00 g) and 4-methoxybenzyl chloride (2.85 mL) and by the reaction and treatment in the same manner as in Preparation Example 51, the title compound (3.13 g) was obtained.

Workup

  1. customby the reaction and treatment in the same manner
  2. customas in Preparation Example 51

Sources & evidence

ORD record
ord-cc6e8399b745460798f09d9af50196dc
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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