HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone → HCID 71252136, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484626 | — |
| Reactant | HCID 86676750 | HCID 86676750 | — |
| Product | HCID 71252136 | HCID 71252136 | 13% |
Reaction Steps
Using (R)-3-ethylisothiazolidine 1,1-dioxide (150 mg) described in Preparation Example 3 and (4-bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (439 mg) described in Preparation Example 114 and by the reaction and treatment in the same manner as in Example 1, the title compound (60 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-450d8d2d71104b21a85325d289006274 |
| Source note | uspto-grants-2014_08 |