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HRID2411402

反应详情

EQUATION

反应方程式

HRID 2411402 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(N2CCN(C(=O)c3ccc(Br)cc3S(C)(=O)=O)CC2)c(C)c1
HCID58484856

未命名化合物

结构：C[C@@H]1CNS(=O)(=O)C1
HCID86676775

(R)-4-methylisothiazolidine 1,1-dioxide

C4H9NO2S

PRODUCTS

生成物

1
结构：Cc1ccc(N2CCN(C(=O)c3ccc(N4C[C@@H](C)CS4(=O)=O)cc3S(C)(=O)=O)CC2)c(C)c1
HCID71252453

未命名化合物

收率 4.6%

PROCEDURE

实验过程

Using (R)-4-methylisothiazolidine 1,1-dioxide (203 mg) described in Preparation Example 7 and (4-bromo-2-methanesulfonylphenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (451 mg) described in Preparation Example 110 and by the reaction and treatment in the same manner as in Example 1, the title compound (23 mg) was obtained.

WORKUP

后处理

  1. customdescribed in Preparation Example 110 and by the reaction and treatment in the same manner as in Example 1