HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone → HCID 71253187, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484626 | — |
| Reactant | HCID 86676752 | HCID 86676752 | — |
| Product | HCID 71253187 | HCID 71253187 | 11.8% |
Reaction Steps
Using (R)-3-isopropylisothiazolidine 1,1-dioxide (300 mg) described in Preparation Example 8 and (4-bromo-2-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (440 mg) described in Preparation Example 114 and by the reaction and treatment in the same manner as in Example 4, the title compound (63 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-d10b959ffaf847839b80a8f58bc65122 |
| Source note | uspto-grants-2014_08 |