HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Bromopyridin-3-yl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone → HCID 71252086, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Bromopyridin-3-yl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484661 | — |
| Reactant | (S)-4-methylisothiazolidine 1,1-dioxide | HCID 86676774 | — |
| Product | HCID 71252086 | HCID 71252086 | 39.6% |
Reaction Steps
Using (S)-4-methylisothiazolidine 1,1-dioxide (203 mg) described in Preparation Example 4 and (6-bromopyridin-3-yl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (375 mg) described in Preparation Example 127 and by the reaction and treatment in the same manner as in Example 1, the title compound (170 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-ce44d05e7a7141f1bbf3aaddcede7974 |
| Source note | uspto-grants-2014_08 |