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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411471Generated: November 4, 2026

1-(2,4-Xylyl)piperazine → HCID 71252444, compound

https://huagongshe.com/reaction/2411471

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,4-Xylyl)piperazineHCID 70544—
Reactant4-(1,1-Dioxo-1,2-thiazolidin-2-yl)-3-methylbenzoic acidHCID 24688811—
ProductHCID 71252444HCID 7125244454.1%

Reaction Steps

Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-3-methylbenzoic acid (268 mg) described in Preparation Example and 1-(2,4-dimethylphenyl)piperazine (199 mg) and by the reaction and treatment in the same manner as in Example 87, the title compound (242 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-4dfde2b89d0d4e7fac4816a5f9abc740
Source noteuspto-grants-2014_08