HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-methylisothiazolidine 1,1-dioxide → HCID 71252760, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-methylisothiazolidine 1,1-dioxide | HCID 16664802 | — |
| Reactant | [4-(3,5-Dimethylpyridin-2-yl)piperazin-1-yl](2-fluoro-4-iodophenyl)methanone | HCID 71252432 | — |
| Product | HCID 71252760 | HCID 71252760 | 54.3% |
Reaction Steps
Using [4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl](2-fluoro-4-iodophenyl)methanone (439 mg) described in Preparation Example 155 and (R)-3-methylisothiazolidine 1,1-dioxide (135 mg) described in Preparation Example 2 and by the reaction and treatment in the same manner as in Example 1, the title compound (242 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-acb10092a753445b922e3c43f9a898ef |
| Source note | uspto-grants-2014_08 |