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HRID2411519

反应详情

EQUATION

反应方程式

HRID 2411519 的结构方程式

REACTANTS

反应物

2
结构：C[C@@H]1CCS(=O)(=O)N1
HCID16664802

未命名化合物

结构：Cc1cnc(N2CCN(C(=O)c3ccc(I)cc3S(C)(=O)=O)CC2)c(C)c1
HCID71251932

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(N2CCN(C(=O)c3ccc(N4[C@H](C)CCS4(=O)=O)cc3S(C)(=O)=O)CC2)c(C)c1
HCID71252163

未命名化合物

收率 57.3%

PROCEDURE

实验过程

Using [4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl](4-iodo-2-methanesulfonylphenyl)methanone (580 mg) described in Preparation Example 156 and (R)-3-methylisothiazolidine 1,1-dioxide (157 mg) described in Preparation Example 2 and by the reaction and treatment in the same manner as in Example 1, the title compound (337 mg) was obtained.

WORKUP

后处理

  1. customdescribed in Preparation Example 2 and by the reaction and treatment in the same manner as in Example 1