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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411522Generated: October 31, 2026

4-(1,1-Dioxo-1,2-thiazolidin-2-yl)benzoic acid → HCID 71252173, compound

https://huagongshe.com/reaction/2411522

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1,1-Dioxo-1,2-thiazolidin-2-yl)benzoic acidHCID 6625011—
Reactant1-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine hydrochlorideHCID 67381091—
ProductHCID 71252173HCID 7125217352.5%

Reaction Steps

Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoic acid (241 mg) described in Preparation Example 16 and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine hydrochloride (254 mg) described in Preparation Example 82 and by the reaction and treatment in the same manner as in Example 86, the title compound (231 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-64a3fac9ffdd4bbaa77db8273960a451
Source noteuspto-grants-2014_08