(R)-3-methylisothiazolidine 1,1-dioxide → (R)-[4-(2,4-dimethylphenyl)piperazin-1-yl][2-methanesulfonyl-4-(3-methyl-1,1-dioxo-1lambda6-isothiazolidin-2-yl)phenyl]methanone

Participants

Reaction Steps

Using [4-(2,4-dimethylphenyl)piperazin-1-yl](4-iodo-2-methanesulfonylphenyl)methanone (886 mg) described in Preparation Example 157 and (R)-3-methylisothiazolidine 1,1-dioxide (240 mg) described in Preparation Example 2 and by the reaction and treatment in the same manner as in Example 1, the title compound (514 mg) was obtained.

Provenance & Evidence