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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411524Generated: November 1, 2026

4-(1,1-Dioxo-1,2-thiazolidin-2-yl)benzoic acid → HCID 71252109, compound

https://huagongshe.com/reaction/2411524

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1,1-Dioxo-1,2-thiazolidin-2-yl)benzoic acidHCID 6625011—
Reactant1-(3-Cyclopropyl-5-methylpyridin-2-yl)piperazine hydrochlorideHCID 67380775—
ProductHCID 71252109HCID 712521099.5%

Reaction Steps

Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoic acid (241 mg) described in Preparation Example 16 and 1-(3-cyclopropyl-5-methylpyridin-2-yl)piperazine hydrochloride (254 mg) described in Preparation Example 85 and by the reaction and treatment in the same manner as in Example 86, the title compound (42 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-801774ce54c741e98ab0b24ec40cc571
Source noteuspto-grants-2014_08