1-(3,5-Dicyclopropylpyridin-2-yl)piperazine hydrochloride → [4-(3,5-Dicyclopropylpyridin-2-yl)piperazin-1-yl][4-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)-2-fluorophenyl]methanone

Participants

Reaction Steps

Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-2-fluorobenzoic acid (259 mg) described in Preparation Example 23 and 1-(3,5-dicyclopropylpyridin-2-yl)piperazine hydrochloride (280 mg) described in Preparation Example 87 and to by the reaction and treatment in the same manner as in Example 86, the title compound (323 mg) was obtained.

Provenance & Evidence