HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1,1-Dioxo-1,2-thiazolidin-2-yl)benzoic acid → HCID 71252166, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1,1-Dioxo-1,2-thiazolidin-2-yl)benzoic acid | HCID 6625011 | — |
| Reactant | 1-(3,5-Dicyclopropylpyridin-2-yl)piperazine hydrochloride | HCID 67381094 | — |
| Product | HCID 71252166 | HCID 71252166 | 69.3% |
Reaction Steps
Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoic acid (241 mg) described in Preparation Example 16 and 1-(3,5-dicyclopropylpyridin-2-yl)piperazine hydrochloride (280 mg) described in Preparation Example 87 and by the reaction and treatment in the same manner as in Example 86, the title compound (323 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-6578cca6234f448487d82bf12c3beb28 |
| Source note | uspto-grants-2014_08 |