HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 16664802, compound → HCID 71253046, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 16664802 | HCID 16664802 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(3-cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484690 | — |
| Product | HCID 71253046 | HCID 71253046 | 29.3% |
Reaction Steps
Using (4-bromo-2-fluorophenyl)[4-(3-cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]methanone (375 mg) described in Preparation Example 123 and (R)-3-methylisothiazolidine 1,1-dioxide (107 mg) described in Preparation Example 2 and by the reaction and treatment in the same manner as in Example 4, the title compound (122 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-fda9f0feddfd45ab895c0e9372020412 |
| Source note | uspto-grants-2014_08 |