4-(1,1-Dioxo-1lambda6-isothiazolidin-2-ylmethyl)benzoic acid → [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl][4-(1,1-dioxo-1lambda6-isothiazolidin-2-ylmethyl)phenyl]methanone

Participants

Reaction Steps

Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-ylmethyl)benzoic acid (153 mg) described in Preparation Example 18 and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine (196 mg) described in Preparation Example 83 and by the reaction and treatment in the same manner as in Example 87, the title compound (149 mg) was obtained.

Provenance & Evidence