1-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazine → [4-(5-Cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]{4-[1-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)-1-methylethyl]phenyl}methanone

Participants

Reaction Steps

Using 4-[1-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-1-methylethyl]benzoic acid (170 mg) described in Preparation Example 39 and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine (156 mg) described in Preparation Example 83 and by the reaction and treatment in the same manner as in Example 87, the title compound (115 mg) was obtained.

Provenance & Evidence