HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanesultam → HCID 71252336, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanesultam | HCID 642157 | — |
| Reactant | 6-[4-(6-Bromopyridine-3-carbonyl)piperazin-1-yl]-5-methylnicotinonitrile | HCID 58484518 | — |
| Product | HCID 71252336 | HCID 71252336 | 58% |
Reaction Steps
Using 6-[4-(6-bromopyridine-3-carbonyl)piperazin-1-yl]-5-methylnicotinonitrile (200 mg) described in Preparation Example 160 and isothiazolidine 1,1-dioxide (94 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (128 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-e391d53020e34781896a2767c4249781 |
| Source note | uspto-grants-2014_08 |