(3,5-Dimethylpyrazin-2-yl)piperazine hydrochloride → [(3,5-Dimethylpyrazin-2-yl)piperazin-4-yl] {4-[1-(1,1-dioxo-1lambda6-isothiazolidin-2-yl)-1-methylethyl]phenyl}methanone

Participants

Reaction Steps

Using 4-[1-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-1-methylethyl]benzoic acid (100 mg) described in Preparation Example 39 and (3,5-dimethylpyrazin-2-yl)piperazine hydrochloride (81 mg) described in Preparation Example 104 and by the reaction and treatment in the same manner as in Example 86, the title compound (87 mg) was obtained.

Provenance & Evidence