4-(1,1-Dioxo-1lambda6-isothiazolidin-2-ylmethyl)benzoic acid → [4-(1,1-Dioxo-1lambda6-isothiazolidin-2-ylmethyl)phenyl][4-(3,5,6-trimethylpyridin-2-yl)piperazin-1-yl]methanone

Participants

Reaction Steps

Using 4-(1,1-dioxo-1λ6-isothiazolidin-2-ylmethyl)benzoic acid (64 mg) described in Preparation Example 18 and 1-(3,5,6-trimethylpyridin-2-yl)piperazine (51 mg) described in Preparation Example 92 and by the reaction and treatment in the same manner as in Example 87, the title compound (83 mg) was obtained.

Provenance & Evidence