1-Bromo-2-methylpropane → HCID 59586456, compound

Participants

Reaction Steps

Synthesized according to the method of example 10 using 7-(2-methyl-1H-benzimidazol-6-yl)-4-{8-(methyloxy)-7-[(phenylmethyl)oxy]quinazolin-4-yl}-2,3,4,5-tetrahydro-1,4-benzoxazepine (example 1) in step 1 and isobutyl bromide in step 2. 1H NMR (400 MHz, d6-DMSO): 8.48 (s, 1H), 7.96 (s, 1H), 7.83 (m, 3H), 7.63 (d, 1H), 7.52 (d, 1H), 7.04 (d, 1H), 5.46 (s, 2H), 4.65 (br s, 3H) 4.53 (br s, 2H), 4.07 (d, 2H), 3.92 (s, 3H), 2.79 (s, 3H), 2.13 (m, 1H), 1.04 (d, 6H); MS (EI) for C30H31N5O3: 510 (MH+).

Provenance & Evidence