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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411747Generated: November 1, 2026

2-Pyrrolidone → HCID 71252532, compound

https://huagongshe.com/reaction/2411747

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyrrolidoneHCID 12025—
Reactant5-Bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrileHCID 58484628—
ProductHCID 71252532HCID 71252532—

Reaction Steps

Using 5-bromo-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile (399 mg) described in Preparation Example 187 and pyrrolidin-2-one (115 μL) and by the reaction and treatment in the same manner as in Example 262, the title compound (275 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-a958e76eed0e4926b1a38a1b79aad8df
Source noteuspto-grants-2014_08