Methyl iodide → HCID 71252088, compound

HRID 2411765Notes

Reaction equation

HRID 2411765 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([C:15]([C:17]2[CH:22]=[CH:21][C:20]([N:23]3[CH2:27][CH2:26][NH:25][C:24]3=[O:28])=[CH:19][CH:18]=2)=[O:16])[CH2:11][CH2:10]1.[CH3:29]I>>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[N:9]1[CH2:14][CH2:13][N:12]([C:15]([C:17]2[CH:22]=[CH:21][C:20]([N:23]3[CH2:27][CH2:26][N:25]([CH3:29])[C:24]3=[O:28])=[CH:19][CH:18]=2)=[O:16])[CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 71252851HCID 71252851, compound

Product 1

HCID 71252088HCID 71252088, compound

Procedure

Using 1-{4-[4-(2,4-dimethylphenyl)piperazine-1-carbonyl]phenyl}imidazolidin-2-one (100 mg) described in Example 401 and methyl iodide (18 μL) and by the reaction and treatment in the same manner as in Example 36, the title compound (69 mg) was obtained.

Sources & evidence

ORD record
ord-3ffa20d8f4404f2cbe8a49cdc0927f1c
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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