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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411793Generated: November 2, 2026

1-Methylimidazolidin-2-one → HCID 71252626, compound

https://huagongshe.com/reaction/2411793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methylimidazolidin-2-oneHCID 567600—
Reactant5-Bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]benzonitrileHCID 58484573—
ProductHCID 71252626HCID 7125262681.9%

Reaction Steps

Using 5-bromo-2-[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine-1-carbonyl]benzonitrile (425 mg) described in Preparation Example 189 and 1-methylimidazolidin-2-one (120 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (364 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-40a733a5f8af442cb56c2d50ae9d22bf
Source noteuspto-grants-2014_08