HuagongsheHuagongshe Chemistry Print Report · For research reference only
Caprolactam → HCID 71252244, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Caprolactam | HCID 7768 | — |
| Reactant | (4-Bromo-2-methanesulfonylphenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone | HCID 58484856 | — |
| Product | HCID 71252244 | HCID 71252244 | 48.4% |
Reaction Steps
Using (4-bromo-2-methanesulfonylphenyl)[4-(2,4-dimethylphenyl)piperazin-1-yl]methanone (451 mg) described in Preparation Example 110 and azepan-2-one (119 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (234 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-b46bf4aaa0d1433098abec466b0e3336 |
| Source note | uspto-grants-2014_08 |