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HRID2411918

反应详情

EQUATION

反应方程式

HRID 2411918 的结构方程式

REACTANTS

反应物

3
结构：Cc1cnc(N2CCN(C(=O)c3ccc(Br)nc3)CC2)c(C)c1
HCID58484661

未命名化合物

结构：COc1ccc(CN2C(=O)C(C(C)C)N(c3ccc(C(=O)N4CCN(c5ncc(C)cc5C)CC4)cn3)C2=O)cc1
HCID71252561

未命名化合物

结构：COc1ccc(CN2C(=O)NC(C(C)C)C2=O)cc1
HCID71252864

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(N2CCN(C(=O)c3ccc(N4C(=O)NC(=O)C4C(C)C)nc3)CC2)c(C)c1
HCID71252789

未命名化合物

PROCEDURE

实验过程

Using (6-bromopyridin-3-yl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (225 mg) described in Preparation Example 127 and 5-isopropyl-3-(4-methoxybenzyl)imidazolidine-2,4-dione (157 mg) described in Preparation Example 209 and by the reaction and treatment in the same manner as in Example 508, the title compound (138 mg) was obtained via 1-{5-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]pyridin-2-yl}-5-isopropyl-3-(4-methoxybenzyl)imidazolidine-2,4-dione.

WORKUP

后处理

  1. customdescribed in Preparation Example 209 and by the reaction and treatment in the same manner as in Example 508