HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5,5-Trimethylimidazolidine-2,4-dione → HCID 71252353, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5,5-Trimethylimidazolidine-2,4-dione | HCID 237560 | — |
| Reactant | (4-Bromo-2-fluorophenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484842 | — |
| Product | HCID 71252353 | HCID 71252353 | 10.4% |
Reaction Steps
Using (4-bromo-2-fluorophenyl)[4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (167 mg) described in Preparation Example 121 and 3,5,5-trimethylimidazolidine-2,4-dione (63 mg) described in Preparation Example 218 and by the reaction and treatment in the same manner as in Example 536, the title compound (20 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-a423ecf96faf4bdeae60813da5bbb70c |
| Source note | uspto-grants-2014_08 |