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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2411952Generated: November 1, 2026

1-Methylimidazolidin-2-one → HCID 71252192, compound

https://huagongshe.com/reaction/2411952

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methylimidazolidin-2-oneHCID 567600—
Reactant(4-Bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484537—
ProductHCID 71252192HCID 7125219240.5%

Reaction Steps

Using (4-bromo-2-fluorophenyl)[4-(5-ethyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (203 mg) described in Preparation Example 211 and 1-methylimidazolidin-2-one (60 mg) and by the reaction and treatment in the same manner as in Example 511, the title compound (86 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-fff9bbc79d17482d8e9a8237428049e6
Source noteuspto-grants-2014_08