HCID 20445362, compound → HCID 86676791, compound

HRID 2411957Notes

Reaction equation

HRID 2411957 reaction equation
[O:1]=[C:2]1[CH2:6][S:5][CH2:4][N:3]1[C:7]1[CH:15]=[CH:14][C:10]([C:11]([OH:13])=O)=[CH:9][CH:8]=1.[CH3:16][C:17]1[C:18]([N:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)=[N:19][CH:20]=[C:21]([CH3:23])[CH:22]=1>>[CH3:16][C:17]1[C:18]([N:24]2[CH2:25][CH2:26][N:27]([C:11]([C:10]3[CH:9]=[CH:8][C:7]([N:3]4[C:2](=[O:1])[CH2:6][S:5][CH2:4]4)=[CH:15][CH:14]=3)=[O:13])[CH2:28][CH2:29]2)=[N:19][CH:20]=[C:21]([CH3:23])[CH:22]=1

Participants

3

Reactant 2

HCID 20445362HCID 20445362, compoundHCID 584844961-(3,5-Dimethylpyridin-2-yl)piperazine

Product 1

HCID 86676791HCID 86676791, compoundYield 74.4%

Procedure

Using 4-(4-oxothiazolidin-3-yl)benzoic acid (112 mg) and 1-(3,5-dimethylpyridin-2-yl)piperazine (96 mg) described in Preparation Example 79 and by the reaction and treatment in the same manner as in Example 11, the title compound (148 mg) was obtained.

Workup

  1. customdescribed in Preparation Example 79 and by the reaction and treatment in the same manner as in Example 11

Sources & evidence

ORD record
ord-c31d14fb03204fe7876dcc7da555947d
Source dataset
uspto-grants-2014_08
Patent number
US08816079B2

Reaction notes

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