HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Acetylimidazolidinone → [2,4-Bis(2-oxoimidazolidin-1-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Acetylimidazolidinone | HCID 79350 | — |
| Reactant | (2,4-Dibromophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 71251897 | — |
| Product | [2,4-Bis(2-oxoimidazolidin-1-yl)phenyl][4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 71252813 | 26.9% |
Reaction Steps
Using (2,4-dibromophenyl) [4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (258 mg) described in Preparation Example 237 and 1-acetylimidazolidin-2-one (219 mg) and by the reaction and treatment in the same manner as in Example 638, the title compound (71 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-a65243d1f9154ae39be0ef15e31991cc |
| Source note | uspto-grants-2014_08 |