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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2412Generated: October 25, 2026

4-Methoxybenzenesulfonyl chloride → N-(2-cyanophenyl)-4-methoxybenzenesulfonamide

https://huagongshe.com/reaction/2412

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxybenzenesulfonyl chlorideHCID 7401—
Reactant2-AminobenzonitrileHCID 72913—
ProductN-(2-cyanophenyl)-4-methoxybenzenesulfonamideHCID 66967163.7%

Reaction Steps

Using 2-aminobenzonitrile (1.03 g, 8.55 mmol) and 4-methoxybenzenesulfonyl chloride (1.78 g, 8.55 mmol), the procedure of Reference Example 2 was repeated to obtain 1.57 g (63.7%) of the title compound in the form of colorless solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05728835
Source datasetuspto-grants-1998_03
ORD IDord-884108655568491b9b7065118f5c820d
Source noteuspto-grants-1998_03