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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2412002Generated: October 31, 2026

N-Acetylimidazolidinone → HCID 71251924, compound

https://huagongshe.com/reaction/2412002

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-AcetylimidazolidinoneHCID 79350—
Reactant[4-Bromo-2-(1,1-dioxoisothiazolidin-2-yl)phenyl][4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanoneHCID 58484554—
ProductHCID 71251924HCID 7125192460.8%

Reaction Steps

Using [4-bromo-2-(1,1-dioxo-1λ6-isothiazolidin-2-yl)phenyl][4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone (223 mg) described in Preparation Example 240 and 1-acetylimidazolidin-2-one (83 mg) and by the reaction and treatment in the same manner as in Example 638, the title compound (137 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08816079B2
Source datasetuspto-grants-2014_08
ORD IDord-70c6a48eb7f548528c1eaaa7430bae7f
Source noteuspto-grants-2014_08