HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylimidazolidin-2-one → HCID 71253184, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylimidazolidin-2-one | HCID 567600 | — |
| Reactant | (4-Bromo-3-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone | HCID 58484572 | — |
| Product | HCID 71253184 | HCID 71253184 | 65.6% |
Reaction Steps
Using (4-bromo-3-fluorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone (353 mg) described in Preparation Example 125 and 1-methylimidazolidin-2-one (108 mg) and by the reaction and treatment in the same manner as in Example 1, the title compound (243 mg) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08816079B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-771657ec573c42caab5701d98e89714c |
| Source note | uspto-grants-2014_08 |